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FACIAL
VOLUME
RESTORATION.


PAINT THE HAPPINESS.


CLASSIFICATION.

Origin and composition
Fillers may be classified depending on their source as:

  • autologous (e.g., fat, cultured human fibroblasts);
  • collagen (bovine-derived, human-derived from tissue culture);
  • hyaluronic acid (HA) (non-animal stabilised or viscoelastic HA from bacterial fermentation);
  • synthetic or pseudo-synthetic implants (silicone, polymethacrylate microspheres, poly-L-lactic acid, calcium hydroxylapatite microspheres suspended in aqueous polysaccharide gel, alkyl-imide gel polymer).(4)


DURATION.

Depending on their permanence in the body, fillers can be classified as temporary, semi-permanent, and permanent. The first two classes have a different time of duration in the tissue due to the reabsorption, while the permanent fillers are not absorbable.

  • Temporary fillers stay in the tissue for less than a year; they have a temporary effect because they contain materials that are absorbed by the body over time(3). Examples are: fillers based on collagen, hyaluronic acid and calcium hydroxylapatite(2).
  • Semi-permanent fillers stay in the tissue for up to 1–2 years(3). Longer-lasting fillers typically contain substances such as the absorbable synthetic filler known as poly-L-lactic acid(2).
  • Permanent fillers are substances that remain in the tissue more than two years.(3) Permanent fillers include silicone oils, polymethyl methacrylate (PMMA) microspheres, polyacrylamide, and several other materials either alone or formulated in various combinations with absorbable components.
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